室温下无配体体系钯催化苯乙烯氧化反应研究
PDF下载 (22336)赵延超,梁洪泽,骆钧飞*.室温下无配体体系钯催化苯乙烯氧化反应研究[J].宁波大学学报(理工版),2018,31(3):50-54.DOI:
ZHAO Yan-chao,LIANG Hong-ze,LUO Jun-fei*.Ligand-free Pd-catalyzed oxidation of styrenes at room temperature[J].Journal of Ningbo University(Natural Science & Engineering Edition),2018,31(3):50-54.DOI:
| Title: | Ligand-free Pd-catalyzed oxidation of styrenes at room temperature |
| 作者: | 赵延超, 梁洪泽, 骆钧飞* |
| Author(s): | ZHAO Yan-chao, LIANG Hong-ze, LUO Jun-fei* |
| 关键词: | 钯催化; 无配体; Wacker氧化; 苯乙烯; 酮 |
| Keywords: | Pd-catalyzed; ligand-free; Wacker oxidation; styrene; ketone |
| 分类号: | O625.41 |
| 文献标识码: | A |
| 摘要: | 报道了一种操作简单且有效的钯金属催化苯乙烯及其衍生物转化为苯乙酮类化合物的方法. 研究表明, 该反应在温室下, 使用商业化的三氟乙酸钯催化剂以及廉价的过氧叔丁醇水溶液即可实现Wacker氧化, 且无需额外配体稳定或活化催化剂. 该方法具有高官能团兼容性, 且末端脂肪烯烃、双取代末端烯烃以及中间体均可在该条件下转化为相应的酮. |
| Abstract: | A convenient protocol for the oxidation of a styrene to the corresponding methyl ketone was developed. Without the requirement of an extra additive or ligand, this method allows Wacker-type oxidation to proceed efficiently at room temperature in the presence of a commercially available palladium trifluoroacetate catalyst and inexpensive aqueous tert-butyl peroxide. This transformation is highly functional group tolerant. Furthermore, aliphatic alkenes, di-substituted alkenes and internal alkenes could also be converted into the corresponding ketones. |
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| 备注/Memo: | 收稿日期: 2017?10?08. 宁波大学学报（理工版）网址: http://journallg.nbu.edu.cn/ 基金项目: 宁波大学人才引进项目（ZX2016000748）; 宁波大学王宽诚幸福基金. 第一作者: 赵延超（1992－）, 男, 山东济宁人, 在读硕士研究生, 主要研究方向: 合成化学. E-mail: 1976319312@qq.com *通信作者: 骆钧飞（1987－）, 男, 浙江杭州人, 副教授, 主要研究方向: C-H活化. E-mail: luojunfei@nbu.edu.cn 宁波大学学报（理工版）网址：http://journallg.nbu.edu.cn/ |
