注意缺陷多动障碍两种亚型脑血流动力学特征研究
PDF下载 (113)华玖州,张 洁,程 芳.注意缺陷多动障碍两种亚型脑血流动力学特征研究[J].宁波大学学报(理工版),2024,37(1):77-83.DOI:10.20098/j.cnki.1001-5132.2023.0421
HUA Jiuzhou,ZHANG Jie,CHENG Fang.Research on cerebral hemodynamic response under verbal fluency task in two subtypes of ADHD children[J].Journal of Ningbo University(Natural Science & Engineering Edition),2024,37(1):77-83.DOI:10.20098/j.cnki.1001-5132.2023.0421
| Title: | Research on cerebral hemodynamic response under verbal fluency task in two subtypes of ADHD children |
| 作者: | 华玖州, 张 洁, 程 芳 |
| Author(s): | HUA Jiuzhou, ZHANG Jie, CHENG Fang |
| 关键词: | 注意力缺陷多动障碍; 亚型; 注意力特征; 言语流畅性任务; 功能近红外光谱成像仪技术 |
| Keywords: | attention deficit hyperactivity disorder; subtype; attention characteristics; speech fluency tasks; functional near-infrared spectroscopy |
| 分类号: | R749 |
| DOI: | 10.20098/j.cnki.1001-5132.2023.0421 |
| 文献标识码: | A |
| 摘要: | 探讨注意缺陷多动障碍(Attention Deficit and Hyperactive Disorder, ADHD)混合型(ADHD-C)及多动-冲动为主型(ADHD-HI)儿童在言语流畅性任务(Verbal Fluency Task, VFT)中脑血流动力学反应特征及差异. 通过整合视听持续性操作测试将ADHD患儿区分亚型(33名ADHD-C型及36名ADHD-HI型), 之后采用功能近红外光谱成像仪技术(functional Near-Infrared Spectroscopy, fNIRS)测量两组患儿在VFT中前额和左右颞叶血流动力学反应特征, 并计算其积分值与重心值. 结果发现, 在注意力商数上, ADHD-C组得分均低于ADHD-HI组, 差异有统计学意义(P<0.05); 两组亚型患儿视觉得分低于听觉得分, 差异均有统计学意义(P<0.05). 在VFT测试中, ADHD-C组的左右颞叶积分值较ADHD-HI组降低, 差异有统计学意义(P<0.05); 两组亚型患儿左右颞叶的积分值与综合注意商、听觉注意商、视觉注意商均呈显著正相关(P<0.01). 由此可见, ADHD-C与ADHD-HI亚型在完成VFT时的脑左右颞叶的功能存在差异, 且注意力受损越重, 其血流动力学激活程度越低. |
| Abstract: | To investigate the characteristics and differences of cerebral hemodynamic responses in two subtypes of attention deficit and hyperactivity disorder (ADHD) children, combined subtype (ADHD-C) and hyperactive-impulsiveness subtype (ADHD-HI) under verbal fluency tasks (VFT) was used. Children with ADHD were divided into ADHD-C group (n=33) and ADHD-HI group (n=36) by integrated visual and audio continuous performance test (IVA-CPT). Characteristics of hemodynamic response in the prefrontal cortex and bilateral temporal lobes during VFT were measured by functional near-infrared spectroscopy (fNIRS). Their integral values and barycenter values were calculated. In terms of attention quotient, the attention quotient score of ADHD-C group was significantly lower than that of ADHD-HI group (P<0.05). Visual scores of all ADHD children were significantly lower than auditory scores (P<0.05). Integral values of the temporal lobes of ADHD-C type children were significantly lower than that of ADHD-HI type children under VFT test (P<0.05). When two subtypes of ADHD children were under VFT, integral value of temporal lobes was positively correlated with full-scale attention quotient, auditory attention quotient and visual attention quotient (P<0.01). The results demonstrated that the more impaired attention in both ADHD-C and ADHD-HI subtypes is accompanied with the lower hemodynamic activation in the temporal lobes during the VET. |
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| 备注/Memo: | 收稿日期: 2023－04－20. 宁波大学学报（理工版）网址: http://journallg.nbu.edu.cn/ 第一作者: 华玖州, 心理治疗师, 主要研究方向: 精神病学、心理学. E-mail: huajiuzhou@163.com 宁波大学学报（理工版）网址：http://journallg.nbu.edu.cn/ |
