代谢组学在银屑病关节炎中的研究进展
PDF下载 (61)孙晓艳,周琼艳,李玲芝,忻宁昊,江欣雨,马艺钊,张 静,林秉奖,许素玲.代谢组学在银屑病关节炎中的研究进展[J].宁波大学学报(理工版),2024,37(2):108-113.DOI:10.20098/j.cnki.1001-5132.2023.0503
SUN Xiaoyan,ZHOU Qiongyan,LI Lingzhi,XIN Ninghao,JIANG Xinyu,MA Yizhao,ZHANG Jing,LIN Bingjiang,XU Suling.Research progress in metabolomics in psoriasis arthritis[J].Journal of Ningbo University(Natural Science & Engineering Edition),2024,37(2):108-113.DOI:10.20098/j.cnki.1001-5132.2023.0503
| Title: | Research progress in metabolomics in psoriasis arthritis |
| 作者: | 孙晓艳, 周琼艳, 李玲芝, 忻宁昊, 江欣雨, 马艺钊, 张 静, 林秉奖, 许素玲 |
| Author(s): | SUN Xiaoyan, ZHOU Qiongyan, LI Lingzhi, XIN Ninghao, JIANG Xinyu, MA Yizhao, ZHANG Jing, LIN Bingjiang, XU Suling |
| 关键词: | 银屑病关节炎代谢组学; 诊断; 进展; 治疗 |
| Keywords: | psoriatic arthritis; metabolomics; diagnosis; disease progression; treatment |
| 分类号: | R751.05 |
| DOI: | 10.20098/j.cnki.1001-5132.2023.0503 |
| 文献标识码: | A |
| 摘要: | 近年代谢组学已被广泛应用于临床医学研究, 用于寻找生物标志物及疾病早诊早治等领域. 银屑病关节炎的早期诊断可显著改善患者预后, 降低其结构损伤和功能残疾的风险. 为了解现阶段代谢组学在银屑病关节炎中的应用, 分别对银屑病关节炎及代谢组学进行介绍, 并对两者结合的相关研究进行综述, 从疾病诊断、疾病进展和治疗方面梳理代谢组学在银屑病关节炎的研究进展, 并指出当前研究中存在的局限性, 为更好地开展相关研究提供理论依据. |
| Abstract: | Metabolomics has been recently applied in clinical research, in order to identify the biomarkers for early diagnosis and treatment. Early diagnosis of psoriasis arthritis has been shown to significantly improve patient prognosis, along with the reduced risks of structural damage and functional disability. In order to understand the current application of metabolomics in psoriatic arthritis, the application of metabolomics in psoriatic arthritis was reviewed. The research progress of metabolomics in psoriatic arthritis was summarized from three aspects including disease diagnosis, disease progression, and treatment. In addition, the limitations of the application were pointed out. The review was aimed to provide a theoretical basis for better future related research. |
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| 备注/Memo: | 收稿日期: 2023−05−06. 宁波大学学报（理工版）网址: http://journallg.nbu.edu.cn/ 基金项目: 第四轮市医学重点扶植学科（皮肤病学B类）（2022-F23）; 宁波市重大公益类科技项目（2022S065）. 第一作者: 孙晓艳, 硕士/主治医师，主要研究方向: 疾病早期诊断、流行病与卫生统计. E-mail: 983155099@qq.com *通信作者: 许素玲, 主任医师, 主要研究方向: 皮肤恶性肿瘤、过敏性疾病. E-mail: xusuling@nbu.edu.cn 宁波大学学报（理工版）网址：http://journallg.nbu.edu.cn/ |
