甲基苯丙胺依赖与中脑边缘多巴胺神经系统相关研究
PDF下载 (736)陈 群,周文华*.甲基苯丙胺依赖与中脑边缘多巴胺神经系统相关研究[J].宁波大学学报(理工版),2012,25(03):62-66.DOI:
CHEN Qun,ZHOU Wen-hua*.Methamphetamine Dependence and Mesocorticolimbic Dopaminergic System[J].Journal of Ningbo University(Natural Science & Engineering Edition),2012,25(03):62-66.DOI:
| Title: | Methamphetamine Dependence and Mesocorticolimbic Dopaminergic System |
| 作者: | 陈 群, 周文华* |
| Author(s): | CHEN Qun, ZHOU Wen-hua* |
| 关键词: | 甲基苯丙胺; 中脑边缘多巴胺神经系统; 多巴胺受体; 多巴胺转运体 |
| Keywords: | methamphetamine; mesocorticolimbic dopaminergic system; dopamine receptor; dopamine transporter |
| 分类号: | R964 |
| 文献标识码: | A |
| 摘要: | 以甲基苯丙胺为代表的苯胺类中枢兴奋剂滥用问题日益突出, 文章对甲基苯丙胺依赖的 作用途径和机制进行了概述, 包括中脑边缘系统多巴胺神经通路、多巴胺受体、多巴胺转运体及 其他神经递质, 最后提出了当前甲基苯丙胺成瘾治疗研究的主要方向. |
| Abstract: | As one of the amphetamine type stimulants, methamphetamine has been abused widely in China. The methamphetamine dependence is related to the mesocorticolimbic dopaminergic system. This paper describes the mechanisms underlying methamphetamine dependence on the dopamine release, dopamine receptors and dopamine transporter. |
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| 备注/Memo: | 收稿日期: 2012?03?29. 宁波大学学报（理工版）网址: http://3xb.nbu.edu.cn 基金项目: 国家自然科学基金（U1132602, 81071077）; 科技部“十二五”支撑项目（2012BAI01B07）. 第一作者: 陈 群（1971－）, 女, 浙江慈溪人, 硕士/副教授, 主要研究方向: 神经药理学. E-mail: misssqunchen@sina.com *通讯作者: 周文华（1966－）, 男, 浙江余姚人, 博导/教授, 主要研究方向: 药物依赖机制及防治. E-mail: whzhou@vip.163.com 宁波大学学报（理工版）网址：http://journallg.nbu.edu.cn/ |
