精准微创个体化医疗、3D打印及计算机导航技术在骨科临床的研究进展
PDF下载 (494)张雁儒.精准微创个体化医疗、3D打印及计算机导航技术在骨科临床的研究进展[J].宁波大学学报(理工版),2019,32(6):1-5.DOI:
ZHANG Yanru.Application of precision and minimally-invasive individualized therapy, three dimensional printing and computer assisted orthopedics surgery technology in orthopedic clinic[J].Journal of Ningbo University(Natural Science & Engineering Edition),2019,32(6):1-5.DOI:
| Title: | Application of precision and minimally-invasive individualized therapy, three dimensional printing and computer assisted orthopedics surgery technology in orthopedic clinic |
| 作者: | 张雁儒 |
| Author(s): | ZHANG Yanru |
| 关键词: | 精准微创个体化医疗; 3D打印; 有限元分析; 计算机导航技术; 骨科 |
| Keywords: | precision minimally-invasive individualized therapy; 3D printing technology; finite-element analysis; computer assisted orthopedics surgery; orthopedics |
| 分类号: | R604 |
| 文献标识码: | A |
| 摘要: | 随着近年来3D打印、有限元分析及计算机导航技术迅速发展, 为智能精准微创个体化医疗尤其是骨科临床应用提供了路径和方法. 本文首先对当前精准微创的个性化医疗发展趋势, 以及3D打印和有限元分析在骨科的临床应用进行介绍, 并详细探讨了计算机导航技术在骨科中的临床应用价值和存在的不足, 最后对未来3D打印和骨科计算机导航技术的发展趋势进行了展望. |
| Abstract: | In recent years, 3D printing technology, finite-element analysis and computer assisted orthopedics surgery technology develop rapidly. These technologies help the practice of intelligent, accurate, precise, and minimally-invasive individualized therapy, especially for orthopedic clinic. This paper introduces the development of precision, minimally-invasive and personalized medicine firstly. Then the medical application in orthopedics of 3D printing technology and finite-element analysis was discussed. The clinical application value of computer assisted orthopedics surgery technology in orthopedics was discussed in detail. Finally, the weaknesses of the existing 3D printing and computer assisted orthopedics surgery technology were summarized. The potential applications of 3D printing and computer assisted orthopedics surgery technology in the perinatal field were also included |
| 参考文献 /References: | [1].J]. 转化医学杂志, 2015(5):257-260. [2].王海. 新概念“精准医学”的理解和辨析[J]. 中国科技术语, 2018(20):63-65. [3].杨焕明. 对奥巴马版“精准医学”的“精准”解读[J]. 西安交通大学学报(医学版), 2015(6):721-723. [4].Fox J L. Obama catapults patient-empowered precision Medicine[J]. Nature Biotechnology, 2015:33(4):325. [5].黄卫东. 如何理性看待增材制造(3D打印)技术[J]. 新材料产业, 2013(8):9-12. [6].Coelho P G, Fernandes P R, Rodrigues H C, et al. Numerical modeling of bone tissue adaptation: A hierarchical approach for bone apparent density and trabecular structure[J]. Journal of Biomechanics, 2009, 42(7):830-837. [7].Dias M R, Guedes J M, Flanagan C L, et al. Optimization of scaffold design for bone tissue engineering: A computational and experimental study[J]. Medical Engieering and Physics, 2014, 36(4):448-457. [8].US Food and Drug Adiministration. Design control guidance for medical device manufacturers[EB/OL]. [2019-08-12]. http://www.fda.gov/Medicaldevices/device regulationandguidance/guidancedocuments/ucm070627.html. [9].Crawford D C, de Berardino T M, Williams R J. Neocart, An autologous cartilage tissue implant, compared with microfracture for treatment of distal femoral cartilage lesions: An FDA phase-II prospective, randomized clinical trial after two years[J]. The Journal of Bone Joint Surgery, 2012, 94:979-989. [10].Kang H, Hollister S J, LaMarca F, et al. Porous biodegradable lumbar interbody fusion cage design and fabrication using integrated global-local topology optimization with laser sintering[J]. Journal of Biomechanical Engineering, 2013, 135:101013-101018. [11].Newman M K, Cornwall G B. Teaching medical device design using design control[J]. Expert Review of Medical Devices, 2012, 9(1):7-14. [12].Lin C Y, Kikuchi N, Hollister SJ. A novel method for biomaterial scaffold internal architecture design to match bone elastic properties with desired porosity[J]. Journal of Biomechanics, 2004, 37(5):623-636. [13].Emmelmann C, Scheinemann P, Munsch M, et al. Laser additive manufacturing of modified implant surfaces with osseointegrative characteristics[J]. Physics Procedia, 2011, 12(A):375-384. [14].Song Z L, Feng C K, Chiu F Y, et al. The clinical significance of rapid prototyping technique in complex spinal deformity surgery-case sharing and literature review[J]. Formosan Journal of Musculoskeletal Disorders, 2013, 4(3):88-93. [15].Butscher A, Bohner M, Hofmann S, et al. Structural and material approaches to bone tissue engineering in powder-based three-dimensional printing [J]. Acta Biomaterialia, 2013, 7(3):907-920. [16].Murr L E, Martinez E, Amato K N, et al. Fabrication of metal and alloy components by additive manufacturing: Examples of 3D materials science[J]. Journal of Materials Research and Technology, 2012, 1(1):42-54. [17].Leuders S, Thone M, Riemer A, et al. On the mechanical behaviour of titanium alloy TiAl6V4 manufactured by selective laser melting: Fatigue resistance and crack growth performance[J]. International Journal of Fatigue, 2013, 48(6):300-307. [18].Deepak K, Pattanayak A, Fukuda T, et al. Bioactive Ti metal analogous to human cancellous bone: Fabrication by selective laser melting and chemical treatments[J]. Acta Biomaterialia, 2011,7(3):1398-1406. [19].Fukuda A, Takemoto M, Saito T, et al. Osteoinduction of porous Ti implants with a channel structure fabricated by selective laser melting[J]. Acta Biomaterialia, 2011, 7(5): 2327-2336. [20].Matthias F. Clinical and methodological precision of spinal navigation assisted by 3D intraoperative O-arm radiographic imaging technical note[J]. Journal of Neurosurgery: Spine, 2011, 14(4):532-536. [21].Roberts D W, Strohbehn J W, Hatch J F, et al. A frameless stereotaxic integration of computerized tomographic imaging and the operating microscope[J]. Journal of Neurosurgery, 1986, 65(4):545-549. [22].Peters T M. Image-guided surgery: From X-rays to virtual reality[J]. Computer Methods in Biomechanics and Biomedical Engineering, 2001, 4(1):25-57. [23].孙银山. 基于三维超声图像的穿刺手术机器人辅助系统研究[D]. 哈尔滨: 哈尔滨工业大学, 2011. [24].唐佩福. 创伤骨科发展现状与未来趋势[J]. 中华骨与关节外科杂志, 2015(8):11-14. [25].王燎, 戴尅戎. 骨科个体化治疗与打印技术[J]. 医用生物力学, 2014(3):193-199. [26].郭硕. 骨科手术机器人研究进展[J]. 武警医学, 2018 (10):987-990. [27].王成勇, 谢国能, 赵丹娜, 等. 医疗手术机器人发展概况[J]. 工具技术, 2016, 50:3-11. [28].Application of precision and minimally-invasive individualized therapy, three dimensional printing and computer assisted orthopedics surgery technology in orthopedic clinic |
| 备注/Memo: | 收稿日期: 2019-09-07. 宁波大学学报(理工版)网址: http://journallg.nbu.edu.cn/ 基金项目: 宁波市人才引进专项基金(421805070). 作者简介: 张雁儒(1970-), 男, 河南西华人, 教授, 主要研究方向: 创伤骨科. E-mail: zhangyanru@nbu.edu.cn 宁波大学学报(理工版)网址:http://journallg.nbu.edu.cn/ |